| Common name: | NIS1 |
| Defline: | (1 of 1) K06171 - nicastrin (NCSTN); Nicastrin |
| Description: | transmembrane glycoprotein, forms the gamma-secretase complex with presenilin, aph-1 and pen-2; involved in regulated intramembrane proteolysis of type I integral membrane proteins such as the amyloid precursor protein (APP) and Notch; null-allele passenger mutation was isolated (PMID 29743196) |
| Synonyms: | NIS1,g6815.t1 |
| Chromosome: | chromosome 6 |
We did not create a plasmid for this gene.
We did not determine any protein-protein interactions for this gene.
| Insertion Junction | Mutant Strain | Insertion Junction Feature | Confidence (%) | Genome Version |
|---|---|---|---|---|
| CLIP2.029984_1 | CLIP2.029984 | intron | 80 | 6.1 |
| CLIP2.029984_2 | CLIP2.029984 | intron | 80 | 6.1 |
| CLIP2.075250_1 | CLIP2.075250 | 3'UTR | 80 | 6.1 |
| LMJ.RY0402.146573_1 | LMJ.RY0402.146573 | CDS | 73 | 5.5 |
| PFAM: | PF05450 |
| PANTHER: | PTHR21092 PTHR21092:SF0 |
| KEGG_ec: | |
| KEGG_orthology: | K06171 |
| KOG: | KOG2657 |
| Gene ontology terms:: | GO:0016021, GO:0016485 |
| Best arabidopsis TAIR name: | AT3G52640 |
| Best arabidopsis TAIR symbol: | |
| Best arabidopsis TAIR defline: | Zn-dependent exopeptidases superfamily protein |
| Phytozome Locus Page |
Our phenotype screens did not find statistically significant results for this gene.