| Common name: | TOPBP1,DIV21 |
| Defline: | BRC-repeat-containing protein; (1 of 5) PF12738 - twin BRCT domain (PTCB-BRCT) |
| Description: | ts-lethal mutations block DNA replication |
| Synonyms: | Cre12.g515900.t1.1,DIV21,g12726.t1 |
| Chromosome: | chromosome 12 |
We did not create a plasmid for this gene.
We did not determine any protein-protein interactions for this gene.
| Insertion Junction | Mutant Strain | Insertion Junction Feature | Confidence (%) | Genome Version |
|---|---|---|---|---|
| CLIP2.021492_1 | CLIP2.021492 | CDS | 80 | 6.1 |
| CLIP2.050596_1 | CLIP2.050596 | CDS | 80 | 6.1 |
| CLIP2.050596_2 | CLIP2.050596 | CDS | 80 | 6.1 |
| CLIP2.056209_1 | CLIP2.056209 | CDS | 63 | 6.1 |
| LMJ.RY0402.088633_3 | LMJ.RY0402.088633 | CDS | 73 | 5.5 |
| LMJ.RY0402.181247_1 | LMJ.RY0402.181247 | CDS | 73 | 5.5 |
| LMJ.RY0402.211381_1 | LMJ.RY0402.211381 | CDS | 73 | 5.5 |
| PFAM: | PF12738 |
| PANTHER: | PTHR13561 |
| KEGG_ec: | |
| KEGG_orthology: | K10728 |
| KOG: | |
| Gene ontology terms:: | GO:0005622 |
| Best arabidopsis TAIR name: | AT1G77320 |
| Best arabidopsis TAIR symbol: | MEI1 |
| Best arabidopsis TAIR defline: | transcription coactivators |
| Phytozome Locus Page |
Mutants in this gene exhibit a phenotype under the following conditions:
| Cisplatin, screen 1 of 4 ( 95% confidence (FDR = 0.043)) |
| Cisplatin, screen 3 of 4 ( 99% confidence (FDR = 0.0028)) |
Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.
If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.