Gene: Cre16.g682950

Overview

Common name:RAD9
Defline:DNA damage checkpoint protein; (1 of 1) K10994 - cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] (RAD9A)
Description:Forms a sliding clamp complex with Hus1 and Rad1 that mediates repair at sites of DNA damage. Homolog of yeast DDC1 [PMID: 17992532]
Synonyms:g16443.t1
Chromosome:chromosome 16

Protein Localization

A plasmid for expressing Cre16.g682950 tagged with the fluorescent protein Venus and affinity epitope 3xFLAG is available: pLM005-Cre16.g682950-Venus-3xFLAG

No localization data is available in our datasets for this protein.

Protein-Protein Interactions

We did not determine any protein-protein interactions for this gene.

Mutant Strains

Insertion Junction Mutant Strain Insertion Junction Feature Confidence (%) Genome Version
CLIP2.002591_1 CLIP2.002591 CDS 80 6.1
CLIP2.003891_1 CLIP2.003891 CDS 63 6.1
CLIP2.004416_1 CLIP2.004416 CDS 63 6.1
CLIP2.004790_1 CLIP2.004790 CDS 80 6.1
CLIP2.004790_2 CLIP2.004790 CDS 80 6.1
CLIP2.006723_1 CLIP2.006723 intron 80 6.1
CLIP2.006723_2 CLIP2.006723 intron 80 6.1
LMJ.RY0402.043270_1 LMJ.RY0402.043270 intron 95 5.5
LMJ.RY0402.043270_2 LMJ.RY0402.043270 intron 95 5.5
LMJ.RY0402.046759_1 LMJ.RY0402.046759 intron 73 5.5
LMJ.RY0402.050655_1 LMJ.RY0402.050655 CDS 95 5.5
LMJ.RY0402.050655_2 LMJ.RY0402.050655 CDS 95 5.5
LMJ.RY0402.159134_2 LMJ.RY0402.159134 intron 95 5.5
LMJ.RY0402.159134_3 LMJ.RY0402.159134 intron 95 5.5

Gene Annotations

PFAM:PF04139
PANTHER: PTHR15237
KEGG_ec:EC:3.1.11.2
KEGG_orthology:K10994
KOG:
Gene ontology terms::GO:0000075, GO:0000077, GO:0006281, GO:0030896
Best arabidopsis TAIR name:AT3G05480.1
Best arabidopsis TAIR symbol:ATRAD9,RAD9
Best arabidopsis TAIR defline:cell cycle checkpoint control protein family
Phytozome Locus Page

Phenotypes

Mutants in this gene exhibit a phenotype under the following conditions:

Cisplatin, screen 1 of 4 ( 99% confidence (FDR = 0.0014))
Cisplatin, screen 2 of 4 ( 99% confidence (FDR = 0.00056))
Cisplatin, screen 3 of 4 ( 99% confidence (FDR = 0.0005))
Cisplatin, screen 4 of 4 ( 99% confidence (FDR = 0.0028))
Mannitol, screen 1 of 1 ( 75% confidence (FDR = 0.25))
Methyl methanesulfonate, screen 3 of 4 ( 99% confidence (FDR = 0.00078))
Methyl methanesulfonate, screen 4 of 4 ( 99% confidence (FDR = 0.0014))
Mitomycin C, screen 2 of 4 ( 99% confidence (FDR = 0.00016))
Mitomycin C, screen 3 of 4 ( 99% confidence (FDR = 0.0016))
Mitomycin C, screen 4 of 4 ( 99% confidence (FDR = 0.0016))
Zeocin, screen 3 of 5 ( 94% confidence (FDR = 0.051))
Zeocin, screen 4 of 5 ( 98% confidence (FDR = 0.02))
Zeocin, screen 5 of 5 ( 99% confidence (FDR = 0.0011))

Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.

If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.