| Common name: | ATG18 |
| Defline: | (1 of 1) K17908 - autophagy-related protein 18 (WIPI, ATG18); Autophagy related |
| Description: | Phosphoinositide binding protein; required for vesicle formation in autophagy; binds PtdIns(3,5)P2, PI3P and PI4P; WD-40 repeat containing protein and PROPPIN family member; relocalizes from the vacuole to cytoplasm upon DNA replication stress; mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA) |
| Synonyms: | g11225.t1,Cre10.g457550.t1.1 |
| Chromosome: | chromosome 10 |
A plasmid for expressing Cre10.g457550 tagged with the fluorescent protein Venus and affinity epitope 3xFLAG is available: pLM005-Cre10.g457550-Venus-3xFLAG
No localization data is available in our datasets for this protein.
We did not determine any protein-protein interactions for this gene.
| Insertion Junction | Mutant Strain | Insertion Junction Feature | Confidence (%) | Genome Version |
|---|---|---|---|---|
| CLIP2.013306_1 | CLIP2.013306 | CDS | 80 | 6.1 |
| CLIP2.014854_1 | CLIP2.014854 | intron | 80 | 6.1 |
| CLIP2.055064_1 | CLIP2.055064 | intron | 80 | 6.1 |
| CLIP2.065175_1 | CLIP2.065175 | 5'UTR | 80 | 6.1 |
| CLIP2.074980_1 | CLIP2.074980 | intron | 40 | 6.1 |
| CLIP2.078557_1 | CLIP2.078557 | CDS | 63 | 6.1 |
| LMJ.RY0402.150526_1 | LMJ.RY0402.150526 | 3'UTR | 95 | 5.5 |
| LMJ.RY0402.150526_2 | LMJ.RY0402.150526 | CDS | 95 | 5.5 |
| LMJ.RY0402.165794_1 | LMJ.RY0402.165794 | 3'UTR | 95 | 5.5 |
| LMJ.RY0402.165794_2 | LMJ.RY0402.165794 | 3'UTR | 95 | 5.5 |
| PFAM: | PF00400 |
| PANTHER: | PTHR11227 PTHR11227:SF17 |
| KEGG_ec: | |
| KEGG_orthology: | K17908 |
| KOG: | KOG2110 |
| Gene ontology terms:: | GO:0005515 |
| Best arabidopsis TAIR name: | AT4G30510 |
| Best arabidopsis TAIR symbol: | ATATG18B,ATG18B,G18B |
| Best arabidopsis TAIR defline: | homolog of yeast autophagy 18 (ATG18) B |
| Phytozome Locus Page |
Our phenotype screens did not find statistically significant results for this gene.