Gene: Cre10.g467200

Overview

Common name:ATR1
Defline:(1 of 2) PTHR11139:SF69 - SERINE/THREONINE-PROTEIN KINASE ATR; ATM/ATR-related phosphatidylinositol 3-kinase
Description:DNA damage sensing protein kinase homolog; related to ataxia telangiectasia RAD3/ATRprotein. PI3K related
Synonyms:ATR1,g11448.t1
Chromosome:chromosome 10

Protein Localization

We did not create a plasmid for this gene.

Protein-Protein Interactions

We did not determine any protein-protein interactions for this gene.

Mutant Strains

Insertion Junction Mutant Strain Insertion Junction Feature Confidence (%) Genome Version
CLIP2.010630_1 CLIP2.010630 intron 80 6.1
CLIP2.010630_2 CLIP2.010630 intron 80 6.1
CLIP2.018156_1 CLIP2.018156 intron 80 6.1
CLIP2.018156_2 CLIP2.018156 intron 80 6.1
CLIP2.018844_1 CLIP2.018844 CDS 80 6.1
CLIP2.018844_2 CLIP2.018844 CDS 80 6.1
CLIP2.027107_1 CLIP2.027107 intron 80 6.1
CLIP2.027107_2 CLIP2.027107 intron 80 6.1
CLIP2.032775_1 CLIP2.032775 intron 80 6.1
CLIP2.032775_2 CLIP2.032775 intron 80 6.1
LMJ.RY0402.042384_1 LMJ.RY0402.042384 CDS 73 5.5
LMJ.RY0402.076508_1 LMJ.RY0402.076508 intron 58 5.5
LMJ.RY0402.103728_1 LMJ.RY0402.103728 intron 73 5.5
LMJ.RY0402.113831_1 LMJ.RY0402.113831 CDS 58 5.5
LMJ.RY0402.113831_2 LMJ.RY0402.113831 intron 58 5.5
LMJ.RY0402.131757_1 LMJ.RY0402.131757 intron 73 5.5
LMJ.RY0402.171224_1 LMJ.RY0402.171224 intron 73 5.5
LMJ.RY0402.172200_2 LMJ.RY0402.172200 CDS 73 5.5

Gene Annotations

PFAM:PF02259
PANTHER: PTHR11139 PTHR11139:SF69
KEGG_ec:EC:2.7.11.1
KEGG_orthology:K06640
KOG:
Gene ontology terms::GO:0005488, GO:0005515
Best arabidopsis TAIR name:AT5G40820.1
Best arabidopsis TAIR symbol:ATATR,ATR,ATRAD3
Best arabidopsis TAIR defline:Ataxia telangiectasia-mutated and RAD3-related
Phytozome Locus Page

Phenotypes

Mutants in this gene exhibit a phenotype under the following conditions:

Bleomycin sulfate, screen 2 of 2 ( 99% confidence (FDR = 0.00081))
Cisplatin, screen 1 of 4 ( 99% confidence (FDR = 0.0027))
Cisplatin, screen 2 of 4 ( 99% confidence (FDR = 7.1e-10))
Cisplatin, screen 3 of 4 ( 99% confidence (FDR = 1.4e-06))
Cisplatin, screen 4 of 4 ( 99% confidence (FDR = 3.8e-07))
Hydroxyurea, screen 2 of 2 ( 99% confidence (FDR = 0.00093))
Methyl methanesulfonate, screen 1 of 4 ( 98% confidence (FDR = 0.018))
Methyl methanesulfonate, screen 2 of 4 ( 99% confidence (FDR = 2.9e-07))
Methyl methanesulfonate, screen 3 of 4 ( 99% confidence (FDR = 4.4e-07))
Methyl methanesulfonate, screen 4 of 4 ( 99% confidence (FDR = 6.4e-06))
Mitomycin C, screen 1 of 4 ( 73% confidence (FDR = 0.27))
Mitomycin C, screen 2 of 4 ( 99% confidence (FDR = 4.5e-06))
Mitomycin C, screen 3 of 4 ( 99% confidence (FDR = 5.9e-06))
Mitomycin C, screen 4 of 4 ( 99% confidence (FDR = 3.7e-06))
Zeocin, screen 1 of 5 ( 99% confidence (FDR = 2.8e-05))
Zeocin, screen 3 of 5 ( 99% confidence (FDR = 3.9e-06))
Zeocin, screen 4 of 5 ( 99% confidence (FDR = 7.4e-05))
Zeocin, screen 5 of 5 ( 99% confidence (FDR = 8.2e-06))

Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.

If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.