| Common name: | PRP8 |
| Defline: | (1 of 1) K12856 - pre-mRNA-processing factor 8 (PRPF8, PRP8); Splicing factor, component of the U5 snRNP and of the spliceosome |
| Description: | Central component of the spliceosome, which may play a role in aligning the pre-mRNA 5' and 3' exons for ligation. Interacts with U5 snRNA, and with pre-mRNA 5' splice sites in B spliceosomes and 3' splice sites in C spliceosomes. Part of the U5 snRNP complex, and of U5.4/6 and U5.U4atac/U6atac snRNP complexes in U2- and U12-dependent spliceosomes, respectively. ts-lethal mutant isolated (PMID 29743196) |
| Synonyms: | g382.t1,PRP8,Cre01.g016050.t1.1 |
| Chromosome: | chromosome 1 |
We did not create a plasmid for this gene.
We did not determine any protein-protein interactions for this gene.
| Insertion Junction | Mutant Strain | Insertion Junction Feature | Confidence (%) | Genome Version |
|---|---|---|---|---|
| CLIP2.057046_1 | CLIP2.057046 | 3'UTR | 80 | 6.1 |
| CLIP2.058587_1 | CLIP2.058587 | intron | 63 | 6.1 |
| CLIP2.065455_1 | CLIP2.065455 | intron | 63 | 6.1 |
| CLIP2.074195_1 | CLIP2.074195 | intron | 40 | 6.1 |
| CLIP2.074252_1 | CLIP2.074252 | 3'UTR | 80 | 6.1 |
| CLIP2.078822_1 | CLIP2.078822 | intron | 63 | 6.1 |
| LMJ.RY0402.095249_1 | LMJ.RY0402.095249 | intron | 95 | 5.5 |
| LMJ.RY0402.095249_2 | LMJ.RY0402.095249 | intron | 95 | 5.5 |
| LMJ.RY0402.122671_1 | LMJ.RY0402.122671 | intron | 73 | 5.5 |
| PFAM: | PF01398, PF08082, PF08083, PF08084, PF10596, PF10597, PF10598, PF12134 |
| PANTHER: | PTHR11140 PTHR11140:SF0 |
| KEGG_ec: | |
| KEGG_orthology: | K12856 |
| KOG: | KOG1795 |
| Gene ontology terms:: | GO:0000398, GO:0003676, GO:0003723, GO:0005515, GO:0005681, GO:0017070, GO:0030623 |
| Best arabidopsis TAIR name: | AT1G80070 |
| Best arabidopsis TAIR symbol: | EMB14,EMB177,EMB33,SUS2 |
| Best arabidopsis TAIR defline: | Pre-mRNA-processing-splicing factor |
| Phytozome Locus Page |
Our phenotype screens did not find statistically significant results for this gene.