Gene: Cre09.g387400

Overview

Common name:	POLZ1
Defline:	DNA polymerase zeta; (1 of 1) K02350 - DNA polymerase zeta (POLZ1, rev3)
Description:	Homologous to eukaryotic DNA polymerase zeta. Involved in bypass synthesis/translesion synthesis/mutagenic DNA replication; a class B polymerase
Synonyms:	g9557.t1,POLZ1
Chromosome:	chromosome 2 (genome version v6.1), chromosome 9 (genome version v5.5)

Protein Localization

We did not create a plasmid for this gene.

Protein-Protein Interactions

We did not determine any protein-protein interactions for this gene.

Mutant Strains

Insertion Junction	Mutant Strain	Insertion Junction Feature	Confidence (%)	Genome Version
CLIP2.015918_1	CLIP2.015918	CDS	80	6.1
CLIP2.015918_2	CLIP2.015918	CDS	80	6.1
CLIP2.018233_1	CLIP2.018233	intron	80	6.1
CLIP2.020631_1	CLIP2.020631	CDS	80	6.1
CLIP2.020631_2	CLIP2.020631	CDS	80	6.1
CLIP2.027058_1	CLIP2.027058	CDS	80	6.1
CLIP2.027058_2	CLIP2.027058	CDS	80	6.1
CLIP2.033204_1	CLIP2.033204	CDS	80	6.1
CLIP2.033204_2	CLIP2.033204	CDS	80	6.1
CLIP2.043270_1	CLIP2.043270	CDS	80	6.1
CLIP2.043270_2	CLIP2.043270	CDS	80	6.1
LMJ.RY0402.042144_1	LMJ.RY0402.042144	CDS	95	5.5
LMJ.RY0402.042144_2	LMJ.RY0402.042144	CDS	95	5.5
LMJ.RY0402.044293_1	LMJ.RY0402.044293	CDS	95	5.5
LMJ.RY0402.044293_2	LMJ.RY0402.044293	CDS	95	5.5
LMJ.RY0402.064777_1	LMJ.RY0402.064777	3'UTR	73	5.5
LMJ.RY0402.078118_1	LMJ.RY0402.078118	intron	95	5.5
LMJ.RY0402.078118_2	LMJ.RY0402.078118	CDS	95	5.5
LMJ.RY0402.104890_3	LMJ.RY0402.104890	intron	58	5.5
LMJ.RY0402.109016_1	LMJ.RY0402.109016	CDS	58	5.5
LMJ.RY0402.132774_2	LMJ.RY0402.132774	CDS	73	5.5
LMJ.RY0402.166049_1	LMJ.RY0402.166049	CDS	95	5.5
LMJ.RY0402.166049_2	LMJ.RY0402.166049	CDS	95	5.5
LMJ.RY0402.172410_1	LMJ.RY0402.172410	CDS	73	5.5
LMJ.RY0402.182270_1	LMJ.RY0402.182270	intron	95	5.5
LMJ.RY0402.182270_2	LMJ.RY0402.182270	intron	95	5.5
LMJ.RY0402.193684_1	LMJ.RY0402.193684	CDS	95	5.5
LMJ.RY0402.193684_2	LMJ.RY0402.193684	CDS	95	5.5
LMJ.RY0402.202452_1	LMJ.RY0402.202452	CDS	58	5.5
LMJ.RY0402.235139_1	LMJ.RY0402.235139	intron	73	5.5
LMJ.RY0402.242639_1	LMJ.RY0402.242639	intron	58	5.5
LMJ.RY0402.242639_2	LMJ.RY0402.242639	CDS	58	5.5

Gene Annotations

PFAM:	PF00136, PF03104
PANTHER:	PTHR10322 PTHR10322:SF5
KEGG_ec:	EC:2.7.7.7
KEGG_orthology:	K02350
KOG:
Gene ontology terms::	GO:0000166, GO:0003676, GO:0003677, GO:0003887, GO:0006281, GO:0008408, GO:0016035, GO:0019985
Best arabidopsis TAIR name:	AT1G67500.2
Best arabidopsis TAIR symbol:	ATREV3,REV3
Best arabidopsis TAIR defline:	recovery protein 3
Phytozome Locus Page

Phenotypes

Mutants in this gene exhibit a phenotype under the following conditions:

Bleomycin sulfate, screen 1 of 2 ( 77% confidence (FDR = 0.23))

Bleomycin sulfate, screen 2 of 2 ( 98% confidence (FDR = 0.015))

Cisplatin, screen 2 of 4 ( 99% confidence (FDR = 9.1e-16))

Cisplatin, screen 3 of 4 ( 99% confidence (FDR = 6.2e-17))

Cisplatin, screen 4 of 4 ( 99% confidence (FDR = 8e-15))

Methyl methanesulfonate, screen 4 of 4 ( 70% confidence (FDR = 0.3))

Mitomycin C, screen 2 of 4 ( 99% confidence (FDR = 8.2e-24))

Mitomycin C, screen 3 of 4 ( 99% confidence (FDR = 8.4e-21))

Mitomycin C, screen 4 of 4 ( 99% confidence (FDR = 3.9e-21))

UV radiation, screen 2 of 2 ( 99% confidence (FDR = 0.0019))

Zeocin, screen 2 of 5 ( 94% confidence (FDR = 0.053))

Zeocin, screen 3 of 5 ( 98% confidence (FDR = 0.011))

Zeocin, screen 4 of 5 ( 99% confidence (FDR = 6.2e-05))

Zeocin, screen 5 of 5 ( 99% confidence (FDR = 0.007))

Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.

If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.