| Common name: | HUS1 |
| Defline: | DNA damage checkpoint protein; (1 of 1) K10903 - HUS1 checkpoint protein (HUS1) |
| Description: | Forms a sliding clamp complex with Rad9 and Rad1 that mediates repair at sites of DNA damage. |
| Synonyms: | g12910.t1 |
| Chromosome: | chromosome 12 |
A plasmid for expressing Cre12.g524350 tagged with the fluorescent protein Venus and affinity epitope 3xFLAG is available: pLM005-Cre12.g524350-Venus-3xFLAG
No localization data is available in our datasets for this protein.
We did not determine any protein-protein interactions for this gene.
| Insertion Junction | Mutant Strain | Insertion Junction Feature | Confidence (%) | Genome Version |
|---|---|---|---|---|
| CLIP2.000679_1 | CLIP2.000679 | 3'UTR | 80 | 6.1 |
| CLIP2.000679_2 | CLIP2.000679 | 3'UTR | 80 | 6.1 |
| CLIP2.000933_5 | CLIP2.000933 | CDS | 80 | 6.1 |
| CLIP2.000933_6 | CLIP2.000933 | CDS | 80 | 6.1 |
| CLIP2.001632_1 | CLIP2.001632 | intron | 80 | 6.1 |
| CLIP2.001632_2 | CLIP2.001632 | intron | 80 | 6.1 |
| CLIP2.002709_1 | CLIP2.002709 | intron | 80 | 6.1 |
| CLIP2.002709_2 | CLIP2.002709 | intron | 80 | 6.1 |
| CLIP2.004487_1 | CLIP2.004487 | CDS | 80 | 6.1 |
| CLIP2.004487_2 | CLIP2.004487 | CDS | 80 | 6.1 |
| CLIP2.004708_1 | CLIP2.004708 | intron | 80 | 6.1 |
| CLIP2.004708_2 | CLIP2.004708 | intron | 80 | 6.1 |
| LMJ.RY0402.062103_1 | LMJ.RY0402.062103 | intron | 95 | 5.5 |
| LMJ.RY0402.062103_2 | LMJ.RY0402.062103 | intron | 95 | 5.5 |
| LMJ.RY0402.083694_1 | LMJ.RY0402.083694 | intron | 73 | 5.5 |
| LMJ.RY0402.147968_1 | LMJ.RY0402.147968 | intron | 73 | 5.5 |
| LMJ.RY0402.202415_1 | LMJ.RY0402.202415 | intron | 58 | 5.5 |
| LMJ.RY0402.207872_1 | LMJ.RY0402.207872 | intron | 73 | 5.5 |
| LMJ.SG0182.006221_1 | LMJ.SG0182.006221 | intron | 75 | 5.3 |
| PFAM: | PF04005 |
| PANTHER: | PTHR12900 PTHR12900:SF0 |
| KEGG_ec: | |
| KEGG_orthology: | K10903 |
| KOG: | KOG3999 |
| Gene ontology terms:: | GO:0000077, GO:0005730, GO:0006281, GO:0030896 |
| Best arabidopsis TAIR name: | AT1G52530 |
| Best arabidopsis TAIR symbol: | |
| Best arabidopsis TAIR defline: | (1 of 1) PTHR12900 - MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 |
| Phytozome Locus Page |
Mutants in this gene exhibit a phenotype under the following conditions:
| Cisplatin, screen 1 of 4 ( 95% confidence (FDR = 0.043)) |
| Cisplatin, screen 2 of 4 ( 99% confidence (FDR = 0.00056)) |
| Cisplatin, screen 3 of 4 ( 99% confidence (FDR = 0.0025)) |
| Cisplatin, screen 4 of 4 ( 99% confidence (FDR = 0.0048)) |
| Methyl methanesulfonate, screen 3 of 4 ( 97% confidence (FDR = 0.027)) |
| Methyl methanesulfonate, screen 4 of 4 ( 87% confidence (FDR = 0.13)) |
Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.
If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.