Gene: Cre14.g613950

Overview

Common name:ABCA2,ABC2
Defline:(1 of 2) 3.6.3.32 - Quaternary-amine-transporting ATPase; ABC lipid exporter 2
Description:ABCA superfamily; An ABC-family fatty acid transporter; Mutant and overexpressers accumulate respectively less and more TAGs; Protein locates to the ER; Along with ABCA4 (Cre16.g674500), is co-orthologous with ABCA9, ABCA11, and ABCA2 in Arabidopsis thaliana
Synonyms:Cre14.g613950.t1.1,g14793.t2,ABC2
Chromosome:chromosome 14

Protein Localization

We did not create a plasmid for this gene.

Protein-Protein Interactions

Bait ID Bait Name Prey ID Prey Name Reference
Cre02.g097800 HLA3,MRP1 Cre14.g613950 ABCA2,ABC2 Mackinder et al. 2017

Mutant Strains

Insertion Junction Mutant Strain Insertion Junction Feature Confidence (%) Genome Version
CLIP2.013742_1 CLIP2.013742 intron 80 6.1
CLIP2.019620_1 CLIP2.019620 intron 80 6.1
CLIP2.019620_2 CLIP2.019620 intron 80 6.1
CLIP2.022488_1 CLIP2.022488 3'UTR 80 6.1
CLIP2.024703_1 CLIP2.024703 intron 80 6.1
CLIP2.024703_2 CLIP2.024703 intron 80 6.1
CLIP2.028118_1 CLIP2.028118 intron 80 6.1
CLIP2.028118_2 CLIP2.028118 intron 80 6.1
CLIP2.049754_1 CLIP2.049754 intron 80 6.1
CLIP2.049754_2 CLIP2.049754 intron 80 6.1
CLIP2.051649_1 CLIP2.051649 intron 80 6.1
CLIP2.051649_2 CLIP2.051649 intron 80 6.1
LMJ.RY0402.061536_2 LMJ.RY0402.061536 3'UTR 73 5.5
LMJ.RY0402.085740_1 LMJ.RY0402.085740 intron 73 5.5
LMJ.RY0402.097614_1 LMJ.RY0402.097614 intron 73 5.5
LMJ.RY0402.129521_1 LMJ.RY0402.129521 CDS 95 5.5
LMJ.RY0402.129521_2 LMJ.RY0402.129521 CDS 95 5.5
LMJ.RY0402.147678_1 LMJ.RY0402.147678 intron 95 5.5
LMJ.RY0402.147678_2 LMJ.RY0402.147678 intron 95 5.5
LMJ.RY0402.149224_1 LMJ.RY0402.149224 intron 73 5.5
LMJ.RY0402.160375_2 LMJ.RY0402.160375 intron 95 5.5
LMJ.RY0402.160375_3 LMJ.RY0402.160375 intron 95 5.5
LMJ.RY0402.178253_2 LMJ.RY0402.178253 intron 95 5.5
LMJ.RY0402.178253_3 LMJ.RY0402.178253 intron 95 5.5
LMJ.RY0402.209861_1 LMJ.RY0402.209861 CDS 95 5.5
LMJ.RY0402.209861_2 LMJ.RY0402.209861 intron 95 5.5
LMJ.RY0402.219787_1 LMJ.RY0402.219787 3'UTR 95 5.5
LMJ.RY0402.219787_2 LMJ.RY0402.219787 3'UTR 95 5.5
LMJ.RY0402.220543_1 LMJ.RY0402.220543 intron 95 5.5
LMJ.RY0402.220543_2 LMJ.RY0402.220543 intron 95 5.5
LMJ.RY0402.229720_1 LMJ.RY0402.229720 intron 73 5.5
LMJ.RY0402.234807_1 LMJ.RY0402.234807 intron 73 5.5
LMJ.RY0402.237847_2 LMJ.RY0402.237847 intron 73 5.5
LMJ.RY0402.238034_1 LMJ.RY0402.238034 3'UTR 73 5.5
LMJ.SG0182.008667_1 LMJ.SG0182.008667 MULTIPLE_SPLICE_VARIANTS 75 5.3

Gene Annotations

PFAM:PF00005, PF12698
PANTHER: PTHR19229
KEGG_ec:EC:3.6.3.32
KEGG_orthology:
KOG:KOG0059
Gene ontology terms::GO:0005215, GO:0005524, GO:0006810, GO:0016021, GO:0016887
Best arabidopsis TAIR name:AT3G47730
Best arabidopsis TAIR symbol:ABCA2,ATATH1,ATH1
Best arabidopsis TAIR defline:ATP-binding cassette A2
Phytozome Locus Page

Phenotypes

Mutants in this gene exhibit a phenotype under the following conditions:

Paromomycin, screen 6 of 6 ( 79% confidence (FDR = 0.21))

Note: FDR indicates the likelihood that a particular genotype-phenotype relationship is incorrect. Not all mutants in a particular gene show the same phenotype. Please see the mutant pages for each mutant's phenotypes. Complementation is needed to definitively prove a genotype-phenotype link. These data are from a pooled phenotyping experiment.

If you reference the phenotypic data above in a manuscript, please cite: Fauser et al. 2022 Nature Genetics.